Canadian researchers conducted a Phase III randomized trial involving 461 adults with inadequately controlled type 2 diabetes and found that those who received ertugliflozin 5mg/day or 15mg/day experienced a -0.9% and a -1% mean change in glycated A1C from baseline to week 52, respectively, compared with the placebo group. The findings in Diabetes, Obesity and Metabolism revealed that the ertugliflozin group also had reductions in fasting plasma glucose, systolic blood pressure and body weight.
The Glooko Mobile Insulin Dosing System has been cleared by the FDA for long-acting insulin titration for type 2 diabetes patients after a feasibility study found that those who received personalized long-acting insulin dosage treatment plans experienced a drop in average blood glucose levels and an increase in the proportion of readings in-range. Fitted within an app, the system enables clinicians to create customized treatment plans and recommends insulin dose adjustments and analyzes fasting plasma glucose levels.
The National Comprehensive Cancer Network has added Blue Earth Diagnostics' Axumin, or F-18 fluciclovine, injection to its oncology clinical practice guidelines for prostate cancer, recommending the imaging agent be considered for use with either PET/CT or PET/MRI in clinical workups of patients with prostate cancer recurrence or progression. Axumin's inclusion in the NCCN guidelines provides increased validation of its clinical benefit for those with recurrent prostate cancer and can help improve patient access to the radiopharmaceutical, said Blue Earth CEO Jonathan Allis.
Registered dietitian nutritionist Carrie Dennett says most food cravings do not reflect a nutritional need, and instead may be triggered by environmental cues or psychological or emotional needs. Distinguishing cravings from true hunger can be difficult, Dennett says, but cravings usually are more specific, rather than just a general feeling that it is time to eat.
Retail dietitians can answer shoppers' concerns about buying and preparing seafood, including cost and mercury content, said registered dietitian nutritionist Diane Quagliani. In-store promotions can encourage shoppers to stock up on less expensive frozen and canned seafood, while matching different seafoods with the best cooking methods can give people confidence about preparing meals at home.
The CDC said 28 kratom-related salmonella infections have occurred in 20 states, sending 11 people to the hospital, and warned the source has not been identified so people should not consume kratom in any form. The FDA recently said the herbal supplement was like an opioid and Commissioner Scott Gottlieb said there is no evidence it is safe or effective for any medical use.
A study in Diabetes Care showed an association between higher levels of serum xanthine oxidase activity and an increased risk for type 2 diabetes, with women having a higher risk than men. Chinese researchers used a cohort of 4,412 patients ages 30 to 65 and found that xanthine oxidase activity was tied to uric acid concentration, which is linked with obesity and glucose and fructose metabolism.
Riley Hospital for Children in Indianapolis will stop offering hot dogs on patient menus, a decision it said was made before the Physicians Committee for Responsible Medicine launched an ad campaign this week about choking and health hazards linked to the food. The hospital will review whether to keep hot dogs on its public cafeteria menu and the physician group will continue its ad campaign to raise public awareness.
Express Scripts and Walgreens Boots Alliance will add specialty drugs to their group purchasing efforts, with support from ValoremRx Specialty Solutions, to lower costs for patients including those using Walgreens' specialty pharmacy and Express Scripts' Accredo specialty pharmacy. "By expanding our efforts with Walgreens Boots Alliance, we will improve our supply chain and ultimately make the use of these medicines, including biosimilars, more affordable and accessible for our patients and clients," said Tim Wentworth, Express Scripts CEO.
Dr. Alexander Ploss, a molecular biology professor at Princeton University, was awarded a $50,000 Innovation Grant by the New Jersey Health Foundation to finance his research for hepatitis B and hepatitis E treatments.
- Page 1